Modified multi-well plate for biochemical analysis and cell culture experiments

摘要

The invention relates to a modified multi-well plate for biochemical analyzes and cell culture experiments, which is obtainable by a process for functionalization. The process comprises the following process steps: a) treatment of the multi-well plate by means of an ammonia low-pressure plasma so that reactive amino groups are formed on the plate surface; b) applying an aqueous or alcoholic solution of a maleic anhydride copolymer; c) drying the solution of the maleic anhydride copolymer on the surface; d) heat treatment for covalently bonding the maleic anhydride copolymer to the multi-well plate; e) rinsing with aqueous solution to remove unbound and water-soluble maleic anhydride copolymer; f) Heat treatment to restore the reactivity of the anhydride groups on the maleic anhydride copolymer.