NEW INDUSTRY

摘要

The present invention provides indeno[2,1a]indene and isoindolo[2,1-a]indole derivatives of the Formula I, its salts and its stereoisomers, wherein X, RSUB1/SUB, RSUB2/SUB, RSUB3/SUB, RSUB4/SUB, RSUB6/SUB, RSUB7/SUB, RSUB8/SUB, RSUB9/SUB, RSUB11/SUB, RSUB12/SUB, RSUB13 /SUBand RSUB14 /SUBare as described in the specification. The invention also provides a method to prepare the compound of formula I, pharmaceutical composition containing such compounds, and method to manufacture a medicament. These compounds are useful in the treatment of various CNS disorders, hematological disorders, eating disorders, diseases associated with pain, respiratory diseases, genito-urological disorders, cardio vascular diseases and cancer.