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Melanoma-associated antigens, epitopes thereof and melanoma-containing vaccines
Melanoma-associated antigens, epitopes thereof and melanoma-containing vaccines
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机译:黑色素瘤相关抗原,其表位和含黑色素瘤的疫苗
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摘要
The present invention describes a melanoma associated antigen known as gp100. Furthermore, peptides derived form said antigen are claimed. Gp100 and its peptides can be used in vaccines for the treatment of melanoma. Another aspect of the invention are host cells capable of expression of gplOO or the gp100-derived peptides. Furthermor, tumor infiltrating lymphocytes (TIL's) specifically recognizing gp100 are claimed, as are vaccines with these TIL's. Furthermore, diagnostics for the detection of melanoma and for the monitoring of vaccination form part of the invention.
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