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METHOD FOR ACTIVATING NK CELL, METHOD FOR PROLIFERATING AND PRODUCING NK CELL USING THE SAME, AND MONOCYTE CONTAINING NK CELL
METHOD FOR ACTIVATING NK CELL, METHOD FOR PROLIFERATING AND PRODUCING NK CELL USING THE SAME, AND MONOCYTE CONTAINING NK CELL
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机译:激活NK细胞的方法,使用相同细胞增殖和生产NK细胞的方法以及含有NK细胞的单核细胞
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摘要
PROBLEM TO BE SOLVED: To provide a method for activating NK cells by which the NK cells having non-specific cytotoxic activity to various tumor cells, virus-infected cells and the like, or ADCC activity can be activated to safely and simply proliferate without mixing with K562 or the like; a method for proliferating and producing the NK cells using the same; and monocytes containing a large amount of the NK cells.;SOLUTION: In the method for activating the NK cells, the Nk cells are activated by stimulating the monocytes containing T cells and NK cells with a CD52 agonist. The stimulation of the monocytes with the CD52 agonist is carried out in the presence of a cytokine.;COPYRIGHT: (C)2011,JPO&INPIT
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