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METHOD FOR ESTIMATING PROGNOSIS OF RENAL CELL CARCINOMA USING BAC CLONE

机译:BAC克隆评估肾细胞癌预后的方法

摘要

PROBLEM TO BE SOLVED: To provide a new method for determining risk of poor prognosis of renal cell carcinoma which is unpredictable by existing standards such as histological classification.;SOLUTION: The method for detecting the poor prognosis risk of renal cell carcinoma includes (a) a step of preparing a genome DNA derived from a renal tissue of an examinee, (b) a step of examining the presence of methylation of genome DNA prepared in the step (a) in a region relating to the renal cell carcinoma and (c) a step of determining whether the examinee is classified to a poor prognosis group or not from a DNA methylation pattern clarified in the step (b).;COPYRIGHT: (C)2010,JPO&INPIT
机译:要解决的问题:提供一种确定肾细胞癌不良预后风险的新方法,这是现有标准(例如组织学分类)无法预测的;解决方案:检测肾细胞癌不良预后风险的方法包括(a)制备来源于被检查者的肾组织的基因组DNA的步骤,(b)检查在与肾细胞癌有关的区域中和在步骤(a)中制备的基因组DNA的甲基化的步骤,以及根据步骤(b)中阐明的DNA甲基化模式确定受检者是否被归为预后不良的步骤。版权所有:(C)2010,JPO&INPIT

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