USE OF OXY-INDOLE DERIVATIVE IN TREATMENT OF DEMENTIA-ASSOCIATED DISEASE, ALZHEIMER DISEASE AND GLYCOGEN SYNTHASE KINASE-3-ASSOCIATED SYMPTOM

摘要

PPROBLEM TO BE SOLVED: To provide a new compound, a method for producing the same, a new intermediate material used for the production of the same, a medicinal composition containing the above therapeutically active compound, and the method for using the active compound in the treatments, especially in the prevention and/or treatment of dementia-associated diseases, Alzheimer diseases and glycogen synthase kinase-3-associated symptoms. PSOLUTION: This compound which is a free base or its salt, expressed by formula 1 [wherein, RSP1/SPis H; RSP2/SPis carboxy, a 2-6C alkoxycarbonyl or a group RSP4/SPXSP1/SP; RSP3/SPis RSP10/SPXSP2/SP; (m) is 1, 2, 3 or 4; and (n) is 1, 2, 3 or 4] is provided. PCOPYRIGHT: (C)2010,JPO&INPIT