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Use of oxindole derivatives in the treatment of dementia related diseases, Alzheimer's disease and glycogen synthase kinase-3 related symptoms

机译:羟吲哚衍生物在痴呆相关疾病,阿尔茨海默氏病和糖原合酶激酶3相关症状的治疗中的用途

摘要

The present invention relates to a new use of oxindole derivatives of formula I, as a free base or a pharmaceutically acceptable salt thereof, [Chemical formula should be inserted here. Please see paper copy.] wherein R1, R2, R3, m and n are as defined as in claim 1, as well as to new compounds, a process for their preparation and new intermediates used in the preparation thereof, pharmaceutical compositions containing said therapeutically active compounds and to the use of said active compounds in therapy, especially in the prevention and/or treatment of dementia related diseases, Alzheimer's Disease and conditions associated with glycogen synthase kinase-3.
机译:本发明涉及式I的羟吲哚衍生物作为其游离碱或其药学上可接受的盐的新用途,[化学式应在此处插入。请参见纸本副本。]其中R1,R2,R3,m和n如权利要求1所定义,以及新化合物,其制备方法和在其制备中使用的新中间体,含有所述治疗剂的药物组合物活性化合物及其在治疗中的用途,特别是在预防和/或治疗痴呆相关疾病,阿尔茨海默氏病以及与糖原合酶激酶3相关的疾病中的用途。

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