Method of diagnosis and follow-up of bacterial vaginosis by quantitative molecular level

摘要

The present invention relates to a method for follow-up and in vitro diagnosis the condition of the vaginal flora for the presence of bacterial vaginosis, on how to follow-up the therapeutic treatment of bacterial vaginosis in the case as well as necessary. The method, ie b) conditions and a) of at least the following two concentrations of specific sequences that are present as a single copy DNA of Gardnerella vaginalis and bacterial Apotobiumu-Baginae in DNA extracts of vaginal secretions of patients: a) if it meets the concentration Ca of the DNA fragment of Apotobiumu-Baginae derived from 10 ⁸ copies / ml or more, the concentration Cg of the DNA fragments and b) Gardnerella vaginalis derived is 10 ⁹ copies / ml or more I characterized by the failure of the therapeutic treatment of current that is determined or the presence of bacterial vaginosis.