Silk protein-mimicking peptide and composition for preventing or treating cranial nerve disease containing the same (SilkProtein-MickingPeptidesandCompositionsForPreventingCornerNeuropathiesComprisingtheSame)

摘要

The present invention relates to a silk protein-mimicking peptide represented by the following Formula 1, a composition for preventing or treating a brain disease, a composition for improving a brain or cognitive function and a composition for preventing or treating diseases, disorders or conditions associated with oxidative stress comprising the peptide: Gly-Xaa1-Gly-Xaa2 (1) wherein Xaa1 is Ala, Val, Ser, Tyr, Asp, Glu, Thr, Met, Ile, Leu, Phe, His, Lys or Arg; Xaa2 is Ala, Tyr, Val, Ser, Asp, Glu, Thr, Met, Ile, Leu, Phe, His, Lys or Arg; or Xaa2 represents Ala, Tyr, Val, Ser, Asp, Glu, Thr, Met, Ile, Leu, Phe, His, Lys or Arg residue linked to Gly-Xaa3; and Xaa3 is Tyr, Val, Ala, Ser, Asp, Glu, Thr, Met, Ile, Leu, Phe, His, Lys or Arg.