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Being screening manner of the chemical compound which inhibits the formation of screening manner null of the chemical compound which inhibits the formation
Being screening manner of the chemical compound which inhibits the formation of screening manner null of the chemical compound which inhibits the formation
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机译:抑制化合物形成的筛选方式是抑制形成化合物的筛选方式
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摘要
PROBLEM TO BE SOLVED: To provide a method for screening a compound which inhibits the formation of a STAT3, NF-κB p65, and p300 complex.;SOLUTION: This method for screening the compound which inhibits the formation of the STAT3, NF-κB p65, and p300 complex comprises bringing a compound to be tested into contact with a STAT3, NF-κB p65, and p300 complex-dissociated product, lowering the salt concentration of the obtained solution to a salt concentration for forming the STAT3, NF-κB p65, and p300 complex, and then detecting the presence or absence of the formation of the complex with an oligonucleotide probe for detecting the STAT3, NF-κB p65, and p300 complex. Thereby, it is tested whether or not the compound to be tested can inhibit the formation of the STAT3, NF-κB p65, and p300 complex.;COPYRIGHT: (C)2006,JPO&NCIPI
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