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Synthesis of N1- (2'-pyridyl) -1,2-alkanediaminesulfamic acid and its use in the synthesis of biologically active piperazine
Synthesis of N1- (2'-pyridyl) -1,2-alkanediaminesulfamic acid and its use in the synthesis of biologically active piperazine
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机译:N1-(2'-吡啶基)-1,2-链烷二胺氨基磺酸的合成及其在生物活性哌嗪合成中的应用
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摘要
A process for making an N1-(2'-pyridyl)-1,2-alkanediamine sulfamic acid of formula II by reacting a compound of formula I with NH2R'wherein R and R' are as defined in the specification. The invention also includes the compound of formula II, and optical isomers thereof. The compound of formula II is an intermediate useful for making chiral piperazine derivatives which are active at the 5-HT1A receptor.
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