Studies on Acylthiosemicarbazides and Related Heterocycles(ⅪⅤ)——Synthesis and Bactericidal Activity of 1-(5-(3-Pyridyl)-2H-Tetrazol-2-ylacetyl) -4-Arylthiosemicarbazides and 3- (5- (3-Pyridyl)-2H-Tetrazol-2-ylmethyl)-4-Aryl-1,2 ,4-Triazole-5-Thiones

摘要

Introduction In the preceding paper it was described that various 1-acyl-4-substituted thiosemicarbazides and their derivatives exhibited a broad spectrum of antibacterial activities. Kothari pointed out that some heterocycles linked with tetrazole and 1,2,4-triazole can be used as antiinflammatory agent. We have also demonstrated that both 3-(5-a- naphthyl)-2H-tetrazol-2-ylmethyl)-4-aryl-1,2,4-triazole-5-thiones and 3-(3-pyridyl)-