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Cyclic dipeptides and azetidinones and their use in the treatment of CNS injury and neurodegenerative diseases
Cyclic dipeptides and azetidinones and their use in the treatment of CNS injury and neurodegenerative diseases
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机译:环状二肽和氮杂环丁酮及其在中枢神经系统损伤和神经退行性疾病治疗中的应用
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摘要
The present invention provides 4-substituted-2-azetidinone compounds, bicyclic 2-5-diketopiperazine compounds, and pharmaceutical compositions thereof that are potent, safe and effective neuroprotective agents. Due to their strong central nervous system (CNS) activity, the compounds can be used to enhance memory and to treat a variety of neurological disorders. The compounds are particularly useful for treating neurological disorders caused by, or associated with, CNS trauma.
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