Active type hepushijin was designated as index, the diagnostic method of iron metabolic error

摘要

Peculiar serum puroteomupatan of the hemodialysis patient was analyzed surface reinforcement laser desorption ionization duration of flight mass spectrometry (SELDI-TOF-MS) of making use. Level of the serum ferritin three peptides which show significant correlation were discovered in 2,192, 2,789, and 2,851m/z. Molecular size of 2,192 and 2,789m/z respective hepushijin - 20 and - has matched with the size which is reported with 25 well, latter synthetic hepushijin - matched the size of 25 completely. By the fact that physiological active hepushijin in the serum is detected, it is possible to diagnose iron metabolic error.