Therapeutic or preventive agent for intractable diseases with molecular background of oxidative stress cell death

摘要

The therapeutic or preventive agent for intractable diseases having molecular background of oxidative stress cell death according to the present invention has the following general formula (1): wherein R1 is a hydrogen atom and R2 is a C1-C3 alkyl group as a substituent. An optionally substituted C6-C10 aryl group; or R1 and R2 may be bonded to each other to form a tetrahydrofuranyl ring with an adjacent oxygen atom; R3 and R4 are independent of each other; And a C6-C10 aryl C1-C3 alkyl group optionally having a hydrogen atom, a pyridyl group or a halogen atom as a substituent. Or a pharmaceutically acceptable salt thereof as an active ingredient.