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Use of genes identified to be involved in tumor development for the development of anti-cancer drugs and diagnosis of cancer

机译:将已确定参与肿瘤发展的基因用于开发抗癌药物和诊断癌症

摘要

The invention relates to the use of inhibitors of the expressed proteins of the murine genes and/or their human homologues listed in Table 1 for the preparation of a therapeutical composition for the treatment of cancer, in particular for the treatment of solid tumors of lung, colon, breast, prostate, ovarian, pancreas and leukemia and the use of the genes listed in Table 1 for the diagnosis of cancer. The invention also relates to the therapeutical compositions comprising the inhibitors and to methods for development of the inhibitor compounds.
机译:本发明涉及表1中列出的鼠基因和/或其人类同源物的表达蛋白的抑制剂在制备用于治疗癌症,特别是用于治疗肺部实体瘤的治疗组合物中的用途,结肠,乳腺癌,前列腺癌,卵巢癌,胰腺癌和白血病以及表1所列基因在诊断癌症中的用途。本发明还涉及包含抑制剂的治疗组合物以及开发抑制剂化合物的方法。

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