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Peptides Modified with Triterpenoids and Small Organic Molecules: Synthesis and use in Cosmeceuticals

机译:用三萜类化合物和小的有机分子修饰的肽:合成及在药妆中的用途

摘要

The present invention relates to the Synthesis of Triterpenoid peptides and mechanism of action for Anti ageing and skin care. The present invention is directed towards anti-aging skin care compositions comprising peptides which are made by linking herbal actives to a pentapeptide for enhanced anti ageing activity by regenerating the dermal matrix. In detail, the present invention relates to the synthesis of Triterpenoid peptides, providing an enhanced and synergistic activity for reducing the consequences of ageing such as appearance of fine expression lines and wrinkles on the skin by cosmetic modes of application. The Triterpenoid peptides of the present invention with its novel dual action mode can be used for skin ageing & collagen insufficiency. Its Triterpenoid group acts by preventing oxidation and excess activity of serine proteases like elastase and collagenase that result in wrinkling of skin. With added peptides which boost the collagen and other matrix protein, Triterpenoid peptides provide a complete protection against pre mature ageing and functions as a best anti ageing ingredient.
机译:本发明涉及三萜类肽的合成以及抗衰老和皮肤护理的作用机理。本发明涉及包含肽的抗衰老皮肤护理组合物,所述肽通过将草药活性物质连接至五肽而制备,以通过再生真皮基质增强抗衰老活性。详细地,本发明涉及三萜类肽的合成,其提供增强的和协同的活性,以减少衰老的后果,例如通过美容应用方式在皮肤上出现细纹和皱纹。具有其新颖的双重作用模式的本发明的三萜类肽可用于皮肤衰老和胶原蛋白不足。它的三萜类基团通过防止丝氨酸蛋白酶(如弹性蛋白酶和胶原酶)的氧化和过度活性而起作用,从而导致皮肤起皱。通过添加增强胶原蛋白和其他基质蛋白的肽,三萜类肽可提供针对预老化的全面保护,并作为最佳的抗老化成分。

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