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ALTERED BR-3 BINDING POLYPEPTIDES

机译:替代BR-3结合多肽

摘要

The present invention relates to novel BR3 binding antibodies having altered Fc effector function and/or having a mature core carbohydrate structure in the Fc region which lacks fiicose. The present invention also relates to the use of those BR3 binding antibodies and polypeptides in, e.g., methods of treatment, screening methods, diagnostic methods, assays and protein purification methods.
机译:本发明涉及新颖的BR3结合抗体,其具有改变的Fc效应子功能和/或在缺乏丝状糖的Fc区域中具有成熟的核心碳水化合物结构。本发明还涉及那些BR3结合抗体和多肽在例如治疗方法,筛选方法,诊断方法,测定法和蛋白质纯化方法中的用途。

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