首页> 外国专利> Substituted isoquinoline-1,3(2H,4H)-diones, 1-thioxo,1,4-dihydro-2H-isoquinoline-3-ones and 1,4-dihyro-3 (2H)-isoquinolones and methods of use thereof

Substituted isoquinoline-1,3(2H,4H)-diones, 1-thioxo,1,4-dihydro-2H-isoquinoline-3-ones and 1,4-dihyro-3 (2H)-isoquinolones and methods of use thereof

机译：取代的异喹啉-1,3（2 H ，4 H ）-二酮，1-thioxo，1,4-dihydro-2 H -异喹啉-3-酮和1,4-二羟基-3（2 H ）-异喹诺酮及其使用方法

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This invention provides compounds of Formula (I), having the structure; where G¹, G², G³, G⁴, A¹, A², Y¹, Y², L¹, Z, e and f are defined herein, or a pharmaceutically acceptable salt thereof, which are useful for treating or preventing cancer. 展开▼

机译：本发明提供具有结构的式（I）化合物; 其中G ^{1 ，G ^{2 ，G ^{3 ，G ^{4 ，A ^{1 ，A ^{2 ，Y ^{1 ，Y ^{2 ，L ^{本文定义了1 ，Z，e和f，或其药学上可接受的盐，它们可用于治疗或预防癌症。}}}}}}}}} 展开▼

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公开/公告号US7713994B2

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公开/公告日2010-05-11

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申请/专利权人 HWEI-RU TSOU;SEMIRAMIS AYRAL-KALOUSTIAN;GARY HAROLD BIRNBERG;MIDDLETON BRAWNER FLOYD;JOSHUA KAPLAN;KRISTINA M. KUTTERER;XIAOXIANG LIU;RAMASWAMY NILAKANTAN;MERCY ADUFA OTTENG;ZHILIAN TANG;ARIE ZASK;TRITIN TRAN;SCOTT CHRISTIAN MAYER;ANNETTE L. BANKER;MARVIN REICH;
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申请/专利号US20070728897

发明设计人 HWEI-RU TSOU;SEMIRAMIS AYRAL-KALOUSTIAN;GARY HAROLD BIRNBERG;MIDDLETON BRAWNER FLOYD;JOSHUA KAPLAN;KRISTINA M. KUTTERER;XIAOXIANG LIU;RAMASWAMY NILAKANTAN;MERCY ADUFA OTTENG;ZHILIAN TANG;ARIE ZASK;TRITIN TRAN;SCOTT CHRISTIAN MAYER;ANNETTE L. BANKER;MARVIN REICH;
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申请日2007-03-26

分类号A61K31/47;C07D217/08;

国家 US

入库时间 2022-08-21 18:52:05

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7. High Resolution Electronic Spectroscopy of Para-Alkyl Substituted Phenols and Tetramethyl Cyclobutane-1,3-Dione [R] . Song, K. 1988

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