SUBSTITUTED ISOQUINOLINE-1,3(2H,4H)-DIONES, 1-THIOXO-1,4-DIHYDRO-2H-ISOQUINOLINE-3-ONES AND 1,4-DIHYDRO-3(2H)-ISOQUINOLONES AND USE THEREOF AS KINASE INHIBITOR

摘要

This invention provides compounds of Formula (I), having the structure where GSUP1/SUP, GSUP2/SUP, GSUP3/SUP, GSUP4/SUP, ASUP1/SUP, ASUP2/SUP, YSUP1/SUP, YSUP2/SUP, LSUP1/SUP, Z, e and f are defined herein, or a pharmaceutically acceptable salt thereof, which are useful for treating or preventing cancer.