A method of measuring lung impedance of a subject can include positioning current-injection electrodes on or within the subject in a configuration such that a current injected between the current-injection electrodes propagates substantially through a first lung of the subject, and not through a heart and a second lung of the subject; positioning voltage-measurement electrodes on or within the subject in a configuration such that voltage measuring fields propagate substantially through the first lung and the second lung of the subject, but not through the heart of the subject; and injecting a current between the current-injection electrodes, as positioned, and measuring a resulting voltage between the voltage-measurement electrodes, as positioned, to obtain an impedance measure across lung tissue. The method can further include injecting current and measuring the resulting voltage multiple times over a time period to monitor respiration of the subject over the time period.
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