首页>
外国专利>
Recombinant vector and use in gene therapy
Recombinant vector and use in gene therapy
展开▼
机译:重组载体及其在基因治疗中的应用
展开▼
页面导航
摘要
著录项
相似文献
摘要
A recombinant vector for delivering A3G genes into human cells comprising (i) a gene expression block including an A3G gene selected from a wild type A3G gene represented by SEQ ID NO: 1 and a mutant A3G gene and (ii) a group of elements from a modified lentiviral vector including lentiviral regions of packaging signal (ψ, psi), LTRs, RRE, and PBS; wherein said A3G gene is operably linked to the packaging signal (ψ, psi), LTRs, RRE, and PBS.
展开▼
机译:用于向人细胞中递送A3G基因的重组载体,其包含(i)基因表达块,所述基因表达块包括选自SEQ ID NO:1表示的野生型A3G基因的A3G基因和突变体A3G基因,以及(ii)来自修饰的慢病毒载体,包括包装信号(ψ,psi),LTR,RRE和PBS的慢病毒区域;其中所述A3G基因与包装信号(ψ,psi),LTR,RRE和PBS可操作地连接。
展开▼