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Voltage-gated, pH-sensitive anion channel and its novel splice variant involved in taste sensation
Voltage-gated, pH-sensitive anion channel and its novel splice variant involved in taste sensation
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机译:电压门控,pH敏感的阴离子通道及其涉及味觉的新型剪接变体
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摘要
The invention provides a novel splice-variant of the ClC-4 protein, termed ClC-4A. ClC-4A is expressed in taste bud cells and is involved in sour taste perception. The invention provides ClC-4A polynucleotides and ClC-4A polypeptides, vectors, host cells and ClC-4A specific antibodies as well as designing high potency taste stimuli, determining taste preferences in animals, developing breed-specific foods, and modifying the taste of foods and medications.
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