首页> 外国专利> Azetidin Sulfonamides pyrimidine Derivatives, Pharmaceutical compositions containing the same, Preparation Process and Intermediates of the process, and Use thereof for treating inflammatory and immunological diseases such as Asthma, allergic rhinitis, and arthritis, among others.

Azetidin Sulfonamides pyrimidine Derivatives, Pharmaceutical compositions containing the same, Preparation Process and Intermediates of the process, and Use thereof for treating inflammatory and immunological diseases such as Asthma, allergic rhinitis, and arthritis, among others.

机译:氮杂环丁烷磺酰胺嘧啶衍生物,包含其的药物组合物,其制备方法和该方法的中间体,及其在治疗炎性和免疫性疾病如哮喘,变应性鼻炎和关节炎中的用途。

摘要

A compound of formula (1) and to pharmaceutically acceptable salts for use in the treatment of diseases and conditions mediated by chemokine.Claim 1: a compound as claimed in claim 1 or pharmaceutically acceptable salt is characterized in that a Crystalline forms in any of the following: (a) as a pattern characterized by x-ray Powder diffraction (drxp) as shown and N the Table 3 in this,Named modification; (b) as a pattern characterized by x-ray Powder diffraction (drxp) as shown in Table 4 above in this modification, named B; (c) as a pattern characterized by x-ray Powder diffraction (drxp) as the qu And is shown in Table 5 in this,Named modification C; (d) as a pattern characterized by x-ray Powder diffraction (drxp) as shown in Table 6 in the present modification, named D; (e) as a pattern characterized by x-ray Powder diffraction (drxp) as shown e N the Table 7 in the present,Modification and named; or (f) as a pattern characterized by x-ray Powder diffraction (drxp) as shown in Table 8 in this modification, named F.
机译:权利要求1的化合物或可药用盐,其特征在于,式(1)化合物和可药用盐用于治疗由趋化因子介导的疾病和病症。下列:(a)以特征在于所示的x射线粉末衍射(drxp)和图3中的表3为特征的图案; (b)作为该变型例中的如上表4所示的通过X射线粉末衍射(drxp)表征的图案,称为B; (c)以特征为C的X射线粉末衍射(drxp)为特征的图案如表5所示。 (d)通过X射线粉末衍射(drxp)表征的图案,如本变形例中的表6所示,命名为D; (e)以特征为X射线粉末衍射(drxp)的图案,如本表7中的表N所示,对其进行修改并命名;或(f)以X射线粉末衍射(drxp)为特征的图案,如表8所示,称为F。

著录项

  • 公开/公告号AR072818A1

    专利类型

  • 公开/公告日2010-09-22

    原文格式PDF

  • 申请/专利权人 ASTRAZENECA AB;

    申请/专利号AR2009P102722

  • 申请日2009-07-16

  • 分类号C07D403/12;C07D405/12;C07D239/48;C07D239/69;A61K31/506;A61P11/06;A61P19/02;A61P17/06;A61P37/08;A61P35/00;A61P29/00;

  • 国家 AR

  • 入库时间 2022-08-21 18:47:29

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