USE OF A SEROTONIN 3 (5-HT3) RECEPTOR ANTAGONIST AND A SELECTIVE CHLORIDE CHANNEL MODULATOR FOR THE PREPARATION OF A MEDICAMENT FOR TREATMENT OF DRUG ADDICTION OR DRUG DEPENDENCE OF CENTRAL NERVOUS SYSTEM DISORDERS

摘要

The present invention concerns the use and methods for use of a combination of an antagonist of the serotonin3 receptor (5-HT3), such as ondansetron, and a selective modulator of the chloride channels, such as flumazenil, for treatment of patients with addiction to or dependence on medicines/drugs. Examples of these medicines/drugs include both prescription medicines and illegal drugs, such as, but not exclusively, alcohol, cocaine, nicotine, marijuana, benzodiazepines and opiates. Also, this combination can be used to treat patients suffering from disorders of the central nervous system (CNS), such as, but not exclusively, depression, emotional and mood disorders and memory loss.