首页> 外国专利> IMIDAZOLE DERIVATIVES AS CCR2 RECEPTOR ANTAGONISTS.

IMIDAZOLE DERIVATIVES AS CCR2 RECEPTOR ANTAGONISTS.

机译:咪唑衍生物作为CCR2受体拮抗剂。

摘要

The invention is concerned with novel imidazole derivatives of formula (I), wherein (Ia), m, E, Rsup1/sup, Rsup2/sup, Rsup3/sup, Rsup4/sup, Rsup5/sup, Rsup6/sup and Rsup7/sup are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR- 2 receptor, CCR-5 receptor and/or CCR-3 receptor and can be used as medicaments.
机译:本发明涉及式(I)的新型咪唑衍生物,其中(Ia),m,E,R 1 ,R 2 ,R 3 ,R 4 ,R 5 ,R 6 和R 7 如描述和权利要求及其生理上可接受的盐。这些化合物是CCR-2受体,CCR-5受体和/或CCR-3受体的拮抗剂,可以用作药物。

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