首页> 外国专利> Solid forms of (2S, 3R, 4R, 5S, 6R) - 2 - (4 - chlorine - 3 - (4 - etoxibenzil) phenyl) - 6 - (methylthio) tetrahydro-2h-pyran - 3,4,5 - triol

Solid forms of (2S, 3R, 4R, 5S, 6R) - 2 - (4 - chlorine - 3 - (4 - etoxibenzil) phenyl) - 6 - (methylthio) tetrahydro-2h-pyran - 3,4,5 - triol

机译:(2S,3R,4R,5S,6R)-2-(4-氯-3-(4--依托昔苯)苯基)-6-(甲硫基)四氢-2h-吡喃-3,4,5-三醇的固体形式

摘要

Refers to a Crystalline Compound (2S, 3R, 4R, 5S, 6R) - 2 - (4 - chlorine - 3 - (4 - etoxibenzil) phenyl) - 6 - (methylthio) tetrahydro-2h-pyran - 3,4,5 - triol anhydrous Amorphous characterized with DSC endoterma is close to 124 degrees; an x-ray diffraction pattern with one or more Maximum 4.0 8.1 9.8, 14.0 - Theta - and / or 19.3 degrees 2.It also relates to a preparation method for a Solid Pharmaceutical Form. This Compound is an inhibitor of SGL T2, being useful in the treatment of Metabolic Disorders such as type I and II diabetes, atherosclerosis, obesity, among others
机译:指结晶化合物(2S,3R,4R,5S,6R)-2-(4-氯-3-(4-依托昔苯)苯基)-6-(甲硫基)四氢-2h-吡喃-3,4,5 -无水三醇无定形,特征在于DSC子宫内膜接近124度;具有一个或多个最大4.0 8.1 9.8、14.0-θ和//或19.3度的X射线衍射图。2本发明还涉及固体药物形式的制备方法。该化合物是SGL T2的抑制剂,可用于治疗代谢性疾病,例如I型和II型糖尿病,动脉粥样硬化,肥胖症等

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