FULLY ISOLATED HUMAN ANTI-INTERFERON GAMMA MONOCLONAL ANTIBODY, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF AND METHOD OF AMELIORATION OF A SYMPTOM ASSOCIATED WITH AN IMMUNE-RELATED DISORDER

摘要

The invention relates to fully human antibodies, and fragments thereof, that bind to human interferon gamma (hlFN), thereby modulating the interaction between IFN and its receptor, IFN-R, and/or modulating the biological activities of IFN. The invention also relates to the use of such anti-IFN antibodies in the prevention or treatment of immune-related disorders and in the amelioration of a symptom associated with an immune-related disorder.