IMPROVING LEARNING AND MEMORY AND AMNESIA TREATMENT

摘要

A method for enhancing learning and memory or treating amnesia. The method includes administrating to a subject in need thereof a compound of the formula (I): A is H, R, or each of ArSUB1/SUB, ArSUB2/SUB, and ArSUB3/SUB, independently, is phenyl, thienyl, furyl, or pyrrolyl; each of RSUB1/SUB, RSUB2/SUB, RSUB3/SUB, RSUB4/SUB, RSUB5/SUB, and RSUB6/SUB, independently, is H, nitro, halogen, R, OH, OR, C(O)OH, C(O)OR, C(O)SH, C(O)SR, C(O)NHSUB2/SUB, C(O)NHR, C(O)NRR', ROH, ROR', RSH, RSR', ROC(O)R'OH, NHR, NRR', RNHR', or RNR'R''; or RSUB1 /SUBand RSUB2 /SUBtogether, RSUB3 /SUBand RSUB4 /SUBtogether, or RSUB5 /SUBand RSUB6 /SUBtogether are ORO; wherein each of R, R', and R'', independently is CSUB1/SUB~CSUB6 /SUBalkyl; and n is 1, 2, or 3. The compound is in an effective amount for enhancing learning and memory or treating amnesia.