BENZO-1,2,5-OXADIAZOLES AND BENZO-1,2,5-TIADIAZOLES USEFUL AS HISTOPATHOLOGICAL COLORING AGENTS, IMAGE OBTAINING AGENTS AND BIOMARCATORS.

摘要

A compound of the formula I ** (See formula) ** in which X is O or S, and R1 is 5- (2-fluoroethylamino) -thiazol-2-yl, 5- (2-18F-ethylamino) - thiazol-2-yl or a group of the formula ** (See formula) ** in which Y is C (H) or N, R2 is N (H) CH3, N (H) 11CH3, N (CH3) 11CH3 , N (CH3) 2, N (11CH3) 2, N (H) (CH2) nF, N (H) (CH2) n 18F, N (CH3) (CH2) nF, N (CH3) (CH2) n 18F , O (CH2) nF, O (CH2) n 18F, C (= O) N (H) (CH2) nF or C (= O) N (H) (CH2) n 18F, where n is, in each case, 2, 3 or 4, and R3 is hydroxy, C1-4 alkoxy, hydrogen or nitro, as a free base or as an acid addition salt.