COMBINATION OF A GLICINE TRANSPORTER INHIBITOR (GLYT1) AND AN ANTIPSYCHOTIC FOR THE TREATMENT OF CHYCHOPHRENIA SYMPTOMS AS WELL AS PREPARATION AND USE OF THE SAME.

摘要

A medical product, comprising (a) an antipsychotic selected from the group consisting of risperidone, paliperidone and pharmaceutically acceptable salts thereof, pharmaceutically acceptable esters thereof and enantiomeric forms thereof and (b) a selected GlyT1 inhibitor. among the group consisting of Compound No. 1 ** (See formula) ** Compound No. 2 ** (See formula) ** and pharmaceutically acceptable salts thereof, pharmaceutically acceptable esters thereof and enantiomeric forms thereof; as a combined preparation for simultaneous, separate or sequential use in the treatment or prevention of schizophrenia symptoms associated with disorders such as schizophrenia, dementia, depression, Alzheimer's, ADHD, narcotic abuse and anxiety.