GRANZIMA B DEPENDENT OF PEPTIDES HSP70 / HSP70 AS APOPTOSIS INDUCTOR IN TUMOR CELLS.

摘要

Ex vivo method of inducing or improving the expression of granzyme B in natural killer (NK) cells comprising contacting NK cells with (a) Hsp70 protein; (b) a (C-terminal) fragment of (a) comprising the amino acid sequence TKDNNLLGRFELSG; (c) a (poly) peptide comprising the amino acid sequence TKDNNLLGRFELSG; or (d) a combination of (a), (b) and / or (c).