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GRANZYME B AS AN HSP70/HSP70 PEPTIDE DEPENDENT INDUCER OF APOPTOSIS IN TUMOR CELLS
GRANZYME B AS AN HSP70/HSP70 PEPTIDE DEPENDENT INDUCER OF APOPTOSIS IN TUMOR CELLS
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机译:GRANZYME B作为HSP70 / HSP70肽依赖性肿瘤细胞凋亡的诱导剂
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摘要
The present invention relates to a method of inducing or enhancing the expression of granzyme B in natural killer (NK) cells. The present invention relates also to a use of said NK cells for the preparation of a pharmaceutical composition for the treatment of tumors, viral or bacterial infections or inflammatory diseases. Further, the present invention relates to the use of granzyme B for the treatment of tumors, viral or bacterial infections or inflammatory diseases, wherein the tumor cells or the cells affected by said infection or inflammation express Hsp70 in their cell surface.
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