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correction treatment methods of transcriptome experiments results obtained by differential analysis.

机译:转录组校正处理方法的实验结果通过差异分析获得。

摘要

corrector method carried out by computer processing results of transcriptome experiments obtained by differential analysis, comprising the following steps: - obtaining results of the expression level of genes in a reference condition and calculating the average expression level of each one of said genes; - obtaining results of the expression level of said genes in a processing condition and calculating the average expression level for each of said genes; - calculating the modulation coefficient for the expression level of said genes each; - calculating a p-value associated with each modulation coefficient; - calculating isobaric curves of p-value based on the average expression level of each of said genes in the reference condition; characterized by further comprising a step of calculating and associating a median modulation coefficient on the isobaric curve of each p-value observed.
机译:通过计算机处理通过差异分析获得的转录组实验结果进行校正的方法,包括以下步骤:-获得参考条件下基因表达水平的结果,并计算每个所述基因的平均表达水平; -在加工条件下获得所述基因表达水平的结果,并计算每个所述基因的平均表达水平; -计算每个所述基因的表达水平的调节系数; -计算与每个调制系数相关的p值; -基于参考条件下每个所述基因的平均表达水平,计算p值的等压曲线;其特征在于还包括计算和关联观察到的每个p值的等压曲线上的中值调制系数的步骤。

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