USE OF ANTIBODIES AGAINST MEMBRANE-BOUND FREE LIGHT CHAIN FOR THE TREATMENT OF AUTOIMMUNE DISORDERS

摘要

The present invention relates to the treatment of B-cell mediated immunedisorders such as rheumatoid arthritis,systemic lupus erythromatomus, diabetes mellitus, and multiple sclerosis. Inparticular, the present invention relates to thetreatment of B-cell mediated immune disorders using antibodies which bind tomembrane-bound free light chain expressed on thesurface of plasma cell precursors.