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METHOD FOR PRODUCING A BONE CEMENT WITH BIOACTIVITY AND BONE CEMENT KIT

机译:具有生物活性和骨水泥套件的骨水泥的生产方法

摘要

The invention relates to a method for producing a bone cement with bioactivity and a corresponding bone cement kit. The method comprises mixing a monomer-free polymethylmethacrylate (PMMA) with a mass average molecular weight of 30,000 to 200,000 and an acid number of 10 to 350 mg KOH per g polymer in am amount of 5 to 13 wt. %, with a solvent for PMMA and 40 to 97 wt. % of at least one crystalline and/or glass-crystalline material is added to the mixture with the proviso that the crystalline or glass crystalline material contains 15 - 60 wt.% CaO, 30 - 50 wt.% P2O5, 0 - 9 wt.% ZrO2 and 0 - 3 wt.% fluoride and the mixing and stirring is carried out at a temperature of 10 to 500°C to give a free-flowing mixture with an open processing time in the range 1 to 20 minutes. The addition id preferably of 0.1-10 wt.% ZnO. The material is preferably used as cement or bone filler material in dentistry and as cement for kyphoplasty or vertebroplasty and as fixing cement for joint prostheses.
机译:本发明涉及一种具有生物活性的骨水泥的生产方法和相应的骨水泥套件。该方法包括将质量平均分子量为30,000至200,000且酸值为10至350mg KOH / g聚合物的无单体聚甲基丙烯酸甲酯(PMMA)以5至13重量%的量混合。 %,用PMMA的溶剂和40至97重量%。向混合物中加入至少50重量%的至少一种结晶和/或玻璃结晶材料,条件是该结晶或玻璃结晶材料包含15-60重量%的CaO,30-50重量%的P 2 O 5,0-9重量%。 %的ZrO 2和0〜3重量%的氟化物,并且在10至500℃的温度下进行混合和搅拌,以产生开放处理时间为1至20分钟的自由流动的混合物。添加量优选为0.1-10重量%的ZnO。该材料优选在牙科中用作骨水泥或骨填充材料,并且用于后凸成形术或椎骨成形术的水泥以及用作关节假体的固定水泥。

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