MUTANT FAB FRAGMENTS OF THE CHIMERIC 13B8.2 ANTI-CD4 ANTIBODY AND USES THEREOF

摘要

A mutant Fab fragment of the 13B8.2 anti-CD4 antibody that binds a CD4 molecule and includes a mutation of at least one residue in a position situated in the VH variable domain of the heavy chain and/or in a position situated in the Vkappa variable domain of the light chain.