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METHOD OF PREPARING STANDARD SERUM MIXTURE FOR DETERMINING ACTIVITY OF AN ALLERGEN AND APPLICATION OF THE SERUM MIXTURE

机译:用于确定变应原活性的标准血清混合物的制备方法及血清混合物的应用

摘要

The present invention provides a method for preparing standardized serum mixture for determining allergen potency which comprises: 1) providing multiple serum samples from patients moderately hypersensitive to said allergen; 2) determining the relative content of sIgE against said allergen in each serum sample, obtaining the mean value of the relative content of sIgE of said multiple serum samples, and obtaining deviation value of the relative content of sIgE of each serum with respect to said mean value; 3) removing at least 5% of serum samples that have the largest and smallest deviation values respectively, and mixing the residual sera at the same volume. The invention also relates to the serum mixture prepared by the method as well as the use of such serum mixture.
机译:本发明提供了制备用于确定变应原效力的标准化血清混合物的方法,该方法包括:1)提供来自对所述变应原中等过敏的患者的多个血清样品; 2)确定每个血清样品中相对于所述过敏原的sIgE的相对含量,获得所述多个血清样品中sIgE的相对含量的平均值,并获得每个血清中sIgE的相对含量相对于所述平均值的偏差值值; 3)分别去除至少5%具有最大和最小偏差值的血清样品,并以相同体积混合残留血清。本发明还涉及通过该方法制备的血清混合物以及这种血清混合物的用途。

著录项

  • 公开/公告号EP2124064A4

    专利类型

  • 公开/公告日2010-07-21

    原文格式PDF

  • 申请/专利权人 ZHEJIANG WOLWO BIO-PHARMACEUTICAL CO. LTD.;

    申请/专利号EP20070871769

  • 发明设计人 HU GENGXI;

    申请日2007-12-14

  • 分类号G01N33/96;

  • 国家 EP

  • 入库时间 2022-08-21 18:37:07

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