首页> 外国专利> COMPOSITION COMPRISING BACILLUS CALMETTE GUERIN POLYSACCHARIDES AND BACILLUS CALMETTE GUERIN NUCLEIC ACIDS AND USE OF PREPARING MEDICAMENT THEREOF

COMPOSITION COMPRISING BACILLUS CALMETTE GUERIN POLYSACCHARIDES AND BACILLUS CALMETTE GUERIN NUCLEIC ACIDS AND USE OF PREPARING MEDICAMENT THEREOF

机译:包含芽孢杆菌钙蛋白多糖和芽孢杆菌钙蛋白核酸的组成及其制备药物的用途

摘要

A composition comprising Bacillus Calmette Guerin polysaccharides and Bacillus Calmette Guerin nucleic acids is provided, wherein said polysaccharides are comprising 10%-69% by mass of the composition and said nucleic acids are comprising 30%-89% by mass of the composition. The composition is made by mixing said polysaccharides and said nucleic acids, wherein said polysaccharides and said nucleic acids are obtained from the Bacillus Calmette Guerin cultures by the following process: extracting the mixture of said polysaccharides and said nucleic acids from said Bacillus Calmette Guerin cultures, and separating said polysaccharides and said nucleic acids from the mixture by ion exchange chromatography. The use of the composition comprising said polysaccharides and said nucleic acids for preparation of a biological medicament for treatment or prevention of microorganism infections, tumors, allergic reactions and the like is also provided.
机译:提供了包含卡介苗芽孢杆菌多糖和卡介苗芽孢杆菌核酸的组合物,其中所述多糖占组合物质量的10%-69%,并且所述核酸占组合物质量的30%-89%。通过混合所述多糖和所述核酸来制备所述组合物,其中所述多糖和所述核酸通过以下方法获自卡介苗芽孢杆菌培养物:从所述卡介苗芽孢杆菌培养物中提取所述多糖和核酸的混合物,通过离子交换色谱从混合物中分离所述多糖和核酸。还提供了包含所述多糖和所述核酸的组合物在制备用于治疗或预防微生物感染,肿瘤,变态反应等的生物药物中的用途。

著录项

  • 公开/公告号WO2010081257A1

    专利类型

  • 公开/公告日2010-07-22

    原文格式PDF

  • 申请/专利权人 JIUZHITANG CO. LTD;NING YUNSHAN;GUAN JIFENG;

    申请/专利号WO2009CN00069

  • 发明设计人 NING YUNSHAN;GUAN JIFENG;

    申请日2009-01-16

  • 分类号A61K39/04;A61K31/715;A61K31/7052;A61P31;A61P35;A61P37;A61P37/08;

  • 国家 WO

  • 入库时间 2022-08-21 18:37:06

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