HOOGSTEEN-TYPE TRIPLEX FORMATION OF PYRENE LABELLED PROBES FOR NUCLEIC ACID DETECTION IN FLUORESCENCE ASSAY

摘要

The present invention relates to fluorescent oligonucleotides and methods of providing and using fluorescent oligonucleotides. In particular, the present invention relates to fluorescent oligonucleotides that are capable of triplex formation, said triplex formation resulting in changed fluorescent properties such as to allow detection of triplex formation.