SOLVENT SUPPLY APPARATUS FOR LIQUID CHROMATOGRAPHY MASS SPECTROMETER, REAGENT BOTTLE, SOLVENT AND METHOD FOR SUPPLYING SOLVENT

摘要

Disclosed is a technique whereby, in analyzing proteins and the like by using a liquid chromatography mass spectrometer (LC-MS), a lowering in analysis sensitivity, which is caused by a chemical noise or a lowering in ionization efficiency due to a trace substance contained in a solvent or a trace substance present in the laboratory environment, can be prevented.A solvent supply apparatus (1) for an LC-MS which comprises, for a reagent bottle (2) in which a solvent to be used as a mobile phase in the LC-MS is stored and the opening of which is sealed with a metal foil, an aspiration nozzle (13) which is penetrated through the metal foil and inserted into the reagent bottle so as to suck up the solvent; a vacuum cap (14) which is in contact with the opening of the reagent bottle (2) and cover the same and in which a through hole for penetrating the aspiration nozzle (13) to be inserted into the reagent bottle (2) is formed; and a vacuum pump which is connected to the vacuum cap (14) and sucks up air in the space formed between the vacuum cap (14) covering the opening of the reagent bottle (2) and the metal foil.