BITTER TASTE-MASKED POWDER FORMULATION FOR ORAL SUSPENSION

摘要

PURPOSE: the powder for oral suspension, which has, reduces bitter taste, raising drug compliance is provided to containing azithromycin and L-arginine, by blocking azithromycin bitter taste. ;CONSTITUTION: powder formulation has the L-arginine in the azithromycin (comprising 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin) and 4-60 weight % for reducing bitter taste for oral administration mixed suspension. Form of the powder formulation for oral administration mixed suspension uses or particle. Powder includes the azithromycin of 3-35 weight %, 4-60 weight % L-arginines, and 0.3-0.5 weight % suspending agents, the sweetener of 25-88 weight % and the corrigent of 1-2 weight %. ;The 2010 of copyright KIPO submissions