首页> 外国专利> COMPOSITION COMPRISING THE EXTRACTS OF LEAVES OF LINDERA OBTUSILOBA FOR PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES

COMPOSITION COMPRISING THE EXTRACTS OF LEAVES OF LINDERA OBTUSILOBA FOR PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES

机译：包含杜鹃花叶提取物的化合物，用于预防和治疗心血管疾病

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PURPOSE: one kind is set to dampen NAD (P H oxidizing ferment) and controls contraction and vasodilator smooth muscle containing the anti-mutually Ji cardiovascular disease of Lindera obtusiloba systems. ;CONSTITUTION: a kind of system anti-mutually Ji artery sclerosis, hypertension, reangiostenosis, the failure in the endothelial cell of peripheral artery disease or blood vessel includes 0.The Lindera obtusiloba of 1-99 weight % leave extract as active constituent. The extract is isolated, and uses water, the C1-C5 or their mixture of low wine. Pharmaceutical composition is configured to pulvis, granule, tablet, capsule, suspension, emulsion, syrup, aerosol, external agent, suppository or sterilization injection. ;The 2010 of copyright KIPO submissions

机译：目的：一种可以抑制NAD（PH氧化发酵）并控制收缩和扩张血管的平滑肌的方法，这种平滑肌包含了Lindera obtusiloba系统的抗Ji心血管疾病。组成：一种相互抗吉动脉硬化，高血压，血管再狭窄的系统，外周动脉疾病或血管内皮细胞的破坏包括0。1-99％（重量）的扁桃叶提取物为有效成分。提取物被分离出来，并使用水，C1-C5或它们的低酒混合物。药物组合物被配置为粉剂，颗粒剂，片剂，胶囊剂，混悬剂，乳剂，糖浆剂，气雾剂，外用剂，栓剂或灭菌注射剂。 ; 2010年版权KIPO提交文件

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公开/公告号KR20100002239A

专利类型
公开/公告日2010-01-06

原文格式PDF
申请/专利权人 YANG JI CHEMICAL CO. LTD.;
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申请/专利号KR20090108119
发明设计人 SOHN JUNG DUK;RHEE CHUNG KEUN;LEE JUNG OK;LIM JEE WOONG;OAK MIN HO;CHOI WOON SUN;KIM JONG HOON;
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申请日2009-11-10
分类号A61K36/9068;A61P9/12;A61P9/10;A23L1/30;
国家 KR
入库时间 2022-08-21 18:33:36

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Poster session 2Morphogenetic mechanisms290MiR-133 regulates retinoic acid pathway during early cardiac chamber specification291Bmp2 regulates atrial differentiation through miR-130 during early heart looping formationDevelopmental genetics294Association of deletion allele of insertion/deletion polymorphism in alpha 2B adrenoceptor gene and hypertension with or without type 2 diabetes mellitus295Association of G1359A polymorphism of the endocannabinoid type 1 receptor (CNR1) with coronary artery disease (CAD) with type 2 diabetes mellitusCell growth, differentiation and stem cells - Vascular298Gamma-secretase inhibitor prevents proliferation and migration of ductus arteriosus smooth muscle cells: a role of Notch signaling in postnatal closure of ductus arteriosus299Mesenchymal stromal-like cells (MLCs) derived from induced pluripotent stem (iPS) cells: a promising therapeutic option to promote neovascularization300Sonic Hedgehog promotes mesenchymal stem cell differentiation to vascular smooth muscle cells in cardiovacsular disease301Proinflammatory cytokine secretion and epigenetic modification in endothelial cells treated LPS-GinfivalisCell death and apoptosis - Vascular304Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipidsTranscriptional control and RNA species - Vascular307MicroRNA-34a role in vascular calcification308Local delivery of a miR-146a inhibitor utilizing a clinically applicable approach attenuates neointima formation after vascular injury309Long noncoding RNA landscape of hypoxic endothelial cells310Specific circulating microRNAs levels associate with hypertension, hyperglycemia and dysfunctional HDL in acute coronary syndrome patientsCytokines and cellular inflammation - Vascular313Phosphodiesterase5A up-regulation in vascular endothelium under pro-inflammatory conditions: a newly disclosed anti-inflammatory activity for the omega-3polyunsaturated aatty acid docosahexaenoic acid314Cardiovascular risk modifying with extra-low dose anticytokine drugs in rhematoid arthritis315Conversion of human M-CSF macrophages into foam cells reduces their proinflammatory responses to classical M1-polarizing activation316Lymphocytic myocarditis coincides with increased plaque inflammation and plaque hemorrhage in coronary arteries, facilitating myocardial infarction317Serum osteoprotegerin level predictsdeclined numerous of circulating endothelial- derived and mononuclear-derived progenitor cells in patients with metabolic syndromeGrowth factors and neurohormones - Vascular320Effect of gastrin-releasing peptide (GRP) on vascular inflammationSignal transduction - Heart323A new synthetic peptide regulates hypertrophy in vitro through means of the inhibition of nfkb324Inducible fibroblast-specific knockout of p38 alpha map kinase is cardioprotective in a mouse model of isoproterenol-induced cardiac hypertrophy325Regulation of beta-adrenoceptor-evoked inotropic responses by inhibitory G protein, adenylyl cyclase isoforms 5 and 6 and phosphodiesterases326Binding to RGS3 and stimulation of M2 muscarinic acetylcholine receptors modulates the substrate specificity of p190RhoGAP in cardiac myocytes327Cardiac regulation of post-translational modifications, parylation and deacetylation in LMNA dilated cardiomyopathy mouse model328Beta-adrenergic regulation of the b56delta/pp2a holoenzyme in cardiac myocytes through b56delta phosphorylation at serine 573Nitric oxide and reactive oxygen species - Vascular331Oxidative stress-induced miR-200c disrupts the regulatory loop among SIRT1, FOXO1 and eNOS332Antioxidant therapy prevents oxidative stress-induced endothelial dysfunction and Enhances Wound Healing333Morphological and biochemical characterization of red blood cell in coronary artery diseaseCytoskeleton and mechanotransduction - Heart336Novel myosin activator, JSH compounds, increased myocardial contractility without chronotropic effect in ratsExtracellular matrix and fibrosis - Vascular339Ablation of Toll-like receptor 9 causes cardiac rupture after myocardial infarction by attenuating proliferation and differentiation of cardiac fibroblasts340Altered vascular remodeling in the mouse hind limb ischemia model in Factor VII activating protease (FSAP) deficiencyVasculogenesis, angiogenesis and arteriogenesis343Pro-angiogenic effects of proly-hydroxylase inhibitors and their potential for use in a novel strategy of therapeutic angiogenesis for coronary total occlusion344Nrf2 drives angiogenesis in transcription-independent manner: new function of the master regulator of oxidative stress response345Angiogenic gene therapy, despite efficient vascular growth, is not able to improve muscle function in normoxic or chronically ischemic rabbit hindlimbs -role of capillary arterialization and shunting346Effect of PAR-1 inhibition on collateral vessel growth in the murine hind limb model347Quaking is a key regulator of endothelial cell differentiation, neovascularization and angiogenesis348"Emerging angiogenesis" in the chick chorioallantoic membrane (CAM). 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