COMPOSITION CONTAINING SINGLE INGREDIENT EXTRACTED FROM LAURUS NOBILIS LEAVES FOR PREVENTING AND TREATING NEURODEGENETIVE BRAIN DISEASES AND PARKINSON'S DISEASE

摘要

PURPOSE: A composition for preventing and treating neurodegenerative diseases and Parkinson's disease containing Laurus nobilis leaves is provided to suppress apoptosis and intracellular ROS(reactive oxygen species) and reduce overexpression of active caspase-3 and a-synuclein.;CONSTITUTION: A composition for preventing and treating Parkinson's disease and neurodegenerative disease contains single ingredient isolated from hexane layer and chloroform layer of Laurus nobilis leaves. The single ingredient is costunolide, dehydrocostuslactone or spirafolide, or 3 alpha-acetoxyeudesma-1,4(15),11(13)-triene-12,6alpha-olide. The single ingredient isolated from chloroform layer of Laurus nobilis leaves is reynosin.;COPYRIGHT KIPO 2010