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MC-1R, MC-2R, AND/OR OPIOID RECEPTORS STIMULATION

机译:MC-1R,MC-2R和/或阿片样物质受体刺激

摘要

The invention concerns active substances modulating the expression of the receptors of the products of the POMC gene (MC-IR, MC-2R, and the opioid receptor), and possibly modulating the expression of POMC in cutaneous cells, notably to modulate the proliferation and differentiation of epidermal cells in order to re-epithelial, maintain innervation, irrigate the skin, or to fight against aging, or to modulate pigmentation independently or not of cutaneous aging. The invention also concerns a method of screening such active substances.;COPYRIGHT KIPO & WIPO 2010
机译:本发明涉及调节POMC基因产物的受体(MC-1R,MC-2R和阿片样物质受体)的表达的活性物质,并可能调节皮肤细胞中POMC的表达,特别是调节增殖和增殖。表皮细胞的分化,以重新上皮,维持神经支配,灌溉皮肤或对抗衰老,或独立于或不与皮肤衰老调节色素沉着。本发明还涉及一种筛选此类活性物质的方法。COPYRIGHT KIPO&WIPO 2010

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