METHOD FOR ANALYSIS OF HAPLOTYPE OF CYP2E1

摘要

PURPOSE: A method for analyzing the haplotype of a gene encoding CYP2E1 is provided to analyze SNP(single nucleotide polymorphism) and to develop drugs. CONSTITUTION: A method for analyzing CYP2E1 haplotype comprises: a step of obtaining a promoter, intron 5, intron 6, and exon 7 of a gene encoding CYP2E1 and determining nucleotide sequence thereof; a step of detecting presence of SNP; and a step of identifying the detected SNP. The SNP comprises a mutant in which promoter -1295 locus base G is replaced with base C, a mutant in which promoter -333 locus base T is replaced with base A, and a mutant a codon encoding phenylalanine base C is mutated with base T.