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A COMPOSITION AND METHOD FOR SCREENING ANTI-MALARIAL DRUG BY USING THE ACTIVE FORM OF RECOMBINANT CALPAIN IN PLASMODIUM FALCIPARUM
A COMPOSITION AND METHOD FOR SCREENING ANTI-MALARIAL DRUG BY USING THE ACTIVE FORM OF RECOMBINANT CALPAIN IN PLASMODIUM FALCIPARUM
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机译:利用恶性疟原虫重组钙蛋白活性形式筛选抗疟药的成分和方法
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摘要
PURPOSE: A composition for screening an anti-malaria drug containing calpain of malaria protozoa is provided to apply to develop an agent for preventing and treating malaria. CONSTITUTION: A composition for screening anti-malaria drug contains a calpain gene of P. falciparum. The calpain gene contains a nucleotide of sequence number 3 or base sequence having 90% or more homology with the nucleotide. A composition for screening the anti-malaria drug contains a protein expressed from the calpain gene. The calpain protein has an amino acid sequence of sequence number 4 or amino acid sequence having 90% or more homology with the amino acid. The anti-malaria drug is screened using the composition as a target material.
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