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EMULSIFIED SKIN EXTERNAL PREPARATION AND METHOD FOR STABILIZING THE SKIN EXTERNAL PREPARATION

机译:乳化皮肤外用制剂和稳定皮肤外用制剂的方法

摘要

The present invention is excellent in storage stability of tocopherol glycine to prevent such deterioration occurs in the formulation of viscosity retention provides an emulsified skin external preparation containing an ester derivative. Emulsified skin external preparation is 0.03 to 25 mass% and a tocopherol glycine ester derivative represented by the general formula (1), of the present invention, glycerin mono-fatty acid esters, polyglycerol fatty acid ester and dextrin fatty acid ester at least one fatty acid ester selected from the group consisting of 0.05 should contain about 25 wt% ; & . Formula 1 & ; wherein, R 1 and R 2 , each represent a hydrogen atom or a lower alkyl group but, at the same time there may be a hydrogen atom, R 3 , R 4 and R 5 are each represents a hydrogen atom or a methyl group.
机译:本发明的生育酚甘氨酸的保存稳定性优异,可以防止在粘度保持制剂中发生这种劣化,从而提供含有酯衍生物的乳化皮肤外用剂。乳化皮肤外用剂为0.03〜25质量%,本发明的通式(1)表示的生育酚甘氨酸酯衍生物,甘油单脂肪酸酯,聚甘油脂肪酸酯和糊精脂肪酸酯中的至少一种脂肪族选自0.05的酸酯应含有约25wt%; &。 <式1> ;其中,R 1 和R 2 分别代表氢原子或低级烷基,但同时可能存在氢原子,R 3 ,R 4 和R 5 分别表示氢原子或甲基。

著录项

  • 公开/公告号KR100944593B1

    专利类型

  • 公开/公告日2010-02-25

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20087004556

  • 申请日2006-07-24

  • 分类号A61K8/67;A61K8/44;A61K8/49;

  • 国家 KR

  • 入库时间 2022-08-21 18:31:25

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