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The apparatus and method FLUORESCENT DIAGNOSTICS and photodynamic therapy of skin diseases

机译:该设备和方法荧光诊断和皮肤疾病的光动力疗法

摘要

FIELD: medicine.;SUBSTANCE: device includes power unit and control unit, source of radiation in form of gas-discharge lamp, spectrum-selective chamber for registration of fluorescent images. Gas-discharge lamp is made pulse and is placed in casing provided with light-filters. Light-filters are installed on gas-discharge lamp and have zero light-emission in that spectrum range, in which light-filters of spectrum-selective chamber let through, and light-filters of spectrum-selective chamber have zero light-emission in that spectrum range, in which light-filters of gas-discharge let through. Method of fluorescent diagnostics and photodynamic therapy is realised by means of device, with application of endogenic or induced photosensibilisers of porphyrin group, with application on regions which do not have intensive own fluorescence of applicator, containing 5-aminolevulinic acid for induction of photosensibilisers. Method includes irradiation of affected skin and end of irradiation if concentration of photosensibilisers of porphyrin group decreases lower than therapeutic values. Irradiation and diagnostics are carried out simultaneously by irradiation with pulse light radiation and continuous registration of fluorescent images by means of device.;EFFECT: application of claimed invention allows to increase efficiency of photodynamic therapy realisation and eliminate painful sensations during irradiation process.;2 cl, 8 dwg, 3 ex
机译:领域:药物;物质:该设备包括电源单元和控制单元,气体放电灯形式的辐射源,用于荧光图像配准的光谱选择室。气体放电灯为脉冲式,并置于装有滤光器的外壳中。滤光器安装在气体放电灯上,并且在该光谱范围内具有零发光,其中光谱选择室的滤光器通过,光谱选择室的滤光器在该范围内光谱范围,使气体放电滤光片通过。荧光诊断和光动力疗法的方法是通过使用内源性或诱导的卟啉基光增感剂,并在不具有施加器自身强烈荧光的,含有5-氨基乙酰丙酸的区域用于诱导光增感剂的装置来实现的。如果卟啉组的光敏剂浓度降低到低于治疗值,则方法包括照射患处和照射结束。照射和诊断同时通过脉冲光照射和装置连续记录荧光图像来进行。效果:要求保护的发明的应用允许提高光动力疗法的实现效率并消除照射过程中的痛苦感。2 cl ,8 dwg,3前

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