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Lung cancer detection method using a lung cancer-specific methylation marker gene

机译:使用肺癌特异性甲基化标记基因的肺癌检测方法

摘要

The present invention relates to a method for detecting lung cancer using a lung cancer-specific biomarker, and more particularly to a biomarker for lung cancer diagnosis, which can detect methylation of PCDHGA12 gene whose 5'UTR or exon 1 region is specifically methylated in lung cancer cells, and to a method of detecting lung cancer and the stage of its progression using the biomarker. The diagnostic kit according to the present invention makes it possible to diagnose lung cancer at an early stage in an accurate and rapid manner compared to conventional methods and can be used for prognosis and monitoring of lung cancer and the stage of its progression.
机译:本发明涉及一种使用肺癌特异性生物标记物检测肺癌的方法,更具体地,涉及一种可以检测其5'UTR或外显子1区域在肺中被甲基化的PCDHGA12基因甲基化的肺癌诊断生物标记物。癌细胞,以及使用生物标记物检测肺癌及其进展阶段的方法。与常规方法相比,根据本发明的诊断试剂盒使得可以以准确和快速的方式在早期诊断肺癌,并且可以用于肺癌的预后和监测及其发展阶段。

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